Distinct roles of glutamine metabolism in benign and malignant cartilage tumors with IDH mutations
H. Zhang, V. Puviindran, P. Nadesan, X. Ding, L. Shen, Y. J. Tang, H. Tsushima, Y. Yahara, G. I. Ban, G.-F. Zhang, C. M. Karner, B. A. Alman
This study shows that glutamine metabolism has different roles in benign and malignant cartilage tumors with IDH mutations, suggesting GLS inhibition as a potential therapy for chondrosarcoma.
bioRxiv · Sep 12, 2021Cancer Biology