Author

Y. J. Tang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Bioengineering· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Assay:proteomics· 2

Frequent Co-Authors

J. D. Hebert· 2 shared L. Andrejka· 2 shared M. M. Winslow· 2 shared B. A. Alman· 1 shared C. M. Karner· 1 shared C. R. Detrick· 1 shared D. A. Petrov· 1 shared D. Petrov· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

J. D. Hebert

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Efficient and multiplexed somatic genome editing with Cas12a mice

J. D. Hebert, H. Xu, Y. J. Tang, P. A. Ruiz, C. R. Detrick, J. Wang, N. W. Hughes, O. Donosa, L. Andrejka, S. Karmakar, I. Aboiralor, R. Tang, J. Sage, L. Cong, D. Petrov, M. M. Winslow

This study develops transgenic Cas12a mice to enable efficient, multiplexed somatic genome editing for studying complex genetic interactions in vivo.

bioRxiv · Mar 7, 2024Cancer Biology

Combinatorial in vivo genome editing identifies widespread epistasis during lung tumorigenesis

J. D. Hebert, Y. J. Tang, L. Andrejka, S. S. Lopez, D. A. Petrov, G. Boross, M. M. Winslow

The paper uses in vivo genome editing to study genetic interactions in lung cancer, finding widespread negative epistasis among tumor suppressor genes.

bioRxiv · Mar 7, 2024 · PreprintCancer Biology

Does What You Eat Affect How You Mate? Disentangling the Interactions Between Diet-Induced Phenotypic Plasticity and Adult Reproductive Strategies in Black Soldier Flies.

Q.-H. Zhang, K. H. Ng, W. S. Chin, Y. J. Tang, J. Lin, N. Puniamoorthy

This study examines how larval diets affect adult reproductive strategies and phenotypic plasticity in black soldier flies, revealing sex-specific differences in reproductive investment and mating behaviors.

bioRxiv · Mar 3, 2024Evolutionary Biology

Generative artificial intelligence GPT-4 accelerates knowledge mining and machine learning for synthetic biology

Z. Xiao, W. Li, H. Moon, G. W. Roell, Y. Chen, Y. J. Tang

This paper uses GPT-4 to extract data from synthetic biology papers, creating structured datasets that improve ML predictions for yeast fermentation.

bioRxiv · Jun 14, 2023Bioengineering

Distinct roles of glutamine metabolism in benign and malignant cartilage tumors with IDH mutations

H. Zhang, V. Puviindran, P. Nadesan, X. Ding, L. Shen, Y. J. Tang, H. Tsushima, Y. Yahara, G. I. Ban, G.-F. Zhang, C. M. Karner, B. A. Alman

This study shows that glutamine metabolism has different roles in benign and malignant cartilage tumors with IDH mutations, suggesting GLS inhibition as a potential therapy for chondrosarcoma.

bioRxiv · Sep 12, 2021Cancer Biology