Author

C. M. Karner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. R. Verkerke· 1 shared B. A. Alman· 1 shared C. B. Coleman· 1 shared C. F. Burant· 1 shared C. Wu· 1 shared C.-T. Lin· 1 shared D. G. Mashek· 1 shared E. J. Wentzler· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperPhysiology

A. R. Verkerke

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Author profile →

3 papers

Recent·Most cited

Distinct roles of glutamine metabolism in benign and malignant cartilage tumors with IDH mutations

H. Zhang, V. Puviindran, P. Nadesan, X. Ding, L. Shen, Y. J. Tang, H. Tsushima, Y. Yahara, G. I. Ban, G.-F. Zhang, C. M. Karner, B. A. Alman

This study shows that glutamine metabolism has different roles in benign and malignant cartilage tumors with IDH mutations, suggesting GLS inhibition as a potential therapy for chondrosarcoma.

bioRxiv · Sep 12, 2021Cancer Biology

Hypoxia Depletes Contaminating CD45+ Hematopoietic Cells from Bone Marrow Stromal Cell (BMSC) Cultures: Methods for BMSC Culture Purification

W. Guo, K. V. Spiller, J. Tang, C. M. Karner, M. J. Hilton, C. Wu

This study shows that culturing murine BMSCs under hypoxia reduces hematopoietic contamination and increases stromal cell population.

bioRxiv · Apr 29, 2020Cell Biology

Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity

T. D. Heden, J. M. Johnson, P. J. Ferrara, H. Eshima, A. R. Verkerke, E. J. Wentzler, P. Siripoksup, T. M. Narowski, C. B. Coleman, C.-T. Lin, T. E. Ryan, P. T. Reidy, L. E. de Castro Bras, C. M. Karner, C. F. Burant, , K. Funai

The paper shows that mitochondrial phospholipids, specifically phosphatidylethanolamine (PE), regulate respiratory capacity in skeletal muscle, with PE deficiency causing respiratory failure and oxidative stress.

bioRxiv · Apr 9, 2019Physiology