Type 2 conventional dendritic cells and regulatory T cells form a barrier tissue circuit to control allergic inflammation
Jenny M. Mannion, Lukas M. Altenburger, H. Willit, Neal Patrick Smith, Creel Ng Cashin, Jonah Clegg, Nandini Samanta, Víctor Barrera, William Gammerdinger, Shannan Ho Sui, Caroline L. Sokol, Alexandra–Chloé Villani, Thorsten R. Mempel, Rod A. Rahimi
The paper identifies a cDC2-Treg feedback circuit in barrier tissues that limits Th2 cell expansion during allergic inflammation.
bioRxiv · May 8, 2026 · PreprintImmunology