Shannan Ho Sui

The paper identifies a cDC2-Treg feedback circuit in barrier tissues that limits Th2 cell expansion during allergic inflammation.

This study shows that local IFNγ signaling in aged lungs impairs alveolar progenitor cell regeneration, and reducing IFNγ levels restores regenerative capacity.

The paper performs spatial transcriptomics on the human prefrontal cortex across the lifespan to identify aging-related changes in different cortical layers.

The paper examines how sensory input, sex, and function influence the developmental trajectories of hypothalamic cell types during early life transitions.

The paper uses bulk RNA-Seq to analyze gene expression changes in mouse duodenum and ileum during the first postnatal month, identifying key molecular shifts and comparing them to human data.

This study identifies Pla2g2f as a neuroprotective factor that maintains lipid homeostasis and mitigates aging-associated cognitive decline in a mouse model of Alzheimer's disease.

This study shows that K9me2 and G9a regulate lung progenitor cell activity and regeneration, with their loss altering progenitor dynamics and increasing susceptibility to age-related lung diseases.

The paper shows that Drosophila muscle-derived Pvf1 signals to hepatocyte-like cells to suppress lipid synthesis and prevent obesity.

The paper constructs a cell atlas of the adult Drosophila midgut using scRNA-seq, identifying 12 cell types and providing insights into their molecular features and functions.