Vaccination with single plasmid DNA encoding IL-12 and antigens of severe fever with thrombocytopenia syndrome virus elicits complete protection in IFNAR knockout mice
J.-G. Kang, K. Jeon, H. Choi, Y. Kim, H.-I. Kim, H.-J. Ro, Y. B. Seo, J. Shin, J. Chung, Y. K. Jeon, Y. S. Kim, K. H. Lee, N.-H. Cho
This paper develops a DNA vaccine encoding SFTSV antigens and adjuvants that provides complete protection in IFNAR knockout mice, while protein antigens alone fail to do so.
bioRxiv · Sep 30, 2019Microbiology