Author

H.-R. Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

B. Zhang· 1 shared C. Wu· 1 shared T. Jiang· 1 shared T. Zeng· 1 shared T. Zhang· 1 shared W. Dai· 1 shared X. Chi· 1 shared X. Deng· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

B. Zhang

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1 paper

Recent·Most cited

Targeting oncogenic K-Ras mutants with a small-molecule degrader through Nedd4-1

T. Zeng, T. Jiang, B. Zhang, T. Zhang, W. Dai, X. Yin, Y. Li, C. Wu, Y. Wu, X. Chi, X. Deng, H.-R. Wang

This study develops a small-molecule degrader, XMU-MP-9, that promotes ubiquitination and degradation of K-Ras mutants, including K-RasG12V, by enhancing Nedd4-1 interaction with K-Ras.

bioRxiv · Apr 26, 2024 · PreprintCancer Biology