Salvianolic acids are natural senolytics and increase lifespan in old age
Hongwei Zhang, Zhirui Jiang, Qiang Fu, Qixia Xu, Halidan Wufuer, 周双白, Qingfeng Li, Larissa G. P. Langhi Prata, Guilong Zhang, James L. Kirkland, Yu Sun
This study identifies salvianolic acids as natural senolytics that enhance lifespan and healthspan in aged mice by targeting senescent cells through redox modulation and inducing apoptosis and ferroptosis.
npj Aging · Sep 11, 2026Peer-reviewedCell Biology