Author

Hana El-Samad

Altos Labs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Organism:yeast· 1

Frequent Co-Authors

Aled ParryiD· 1 shared Alice SantambrogioiD· 1 shared Ariane LismeriD· 1 shared C. López· 1 shared Erik J. NavarroiD· 1 shared Francisco M. Martín-ZamoraiD· 1 shared Ignacio Zuleta· 1 shared Ioannis KafetzopoulosiD· 1 shared

Activity by Year

2015-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiophysics

Aled ParryORCID

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2 papers

Recent·Most cited

A Physics-based Model Reveals Mechanisms of Epigenetic Memory

Erik J. Navarro, William Poole, Ariane Lismer, Jieqiong Qu, Ioannis Kafetzopoulos, Aled Parry, Jannat Ijaz, Alice Santambrogio, Ryan Spangler, Francisco M. Martín-Zamora, Ken Raj, Wolf Reik, Hana El-Samad, C. López, Simone Bianco

This paper introduces a physics-based model explaining how cells maintain histone methylation patterns after division, validated by simulations and experimental data.

bioRxiv · Jan 22, 2026 · PreprintBiophysics

Population diversification in a yeast metabolic program promotes anticipation of environmental shifts

Ophelia S Venturelli, Ignacio Zuleta, Richard M Murray, Hana El-Samad

The paper shows that yeast populations activate the galactose pathway before glucose is fully consumed, enabling faster metabolic transitions and a fitness advantage.

PLOS Biology · Jan 27, 2015Peer-reviewedSystems Biology