Hanjeong Harvey

Identification and characterization of new P. aeruginosa phages using a surface receptor platform

The paper introduces a SURFAR platform to identify and characterize new P. aeruginosa phages by targeting specific receptors, isolating two novel phages with distinct host ranges.

The repertoire of resistance mutations selected by a Pseudomonas aeruginosa type IV pilus-targeting lytic bacteriophage

This paper identifies resistance mutations in Pseudomonas aeruginosa exposed to a T4P-targeting phage, showing some mutations allow recovery of pilus function after phage removal.

Structural diversification of phage tail fibres enables recognition of diverse type IV pili

The paper shows how phage tail fibre structure determines their ability to recognize diverse type IV pils despite receptor variation.

Twitching motility suppressors reveal a role for FimX in type IV pilus extension dynamics

The paper identifies suppressor mutations in Pseudomonas aeruginosa that restore twitching motility in fimX mutants, revealing FimX's role in regulating PilB ATP hydrolysis and pilus extension dynamics.

Micro-plaque assays: A high-throughput method to detect, isolate, and characterize bacteriophages

This paper introduces micro-plaque assays to improve phage isolation and characterization, showing they can isolate 21 unique phages from one sample and identify phage susceptibility in clinical strains.