Michael Gordon Surette

Phage HER259 reduces colitis severity caused by AIEC NRG857c and enhances budesonide efficacy in mice.

This study shows antibiotic treatment increases AIEC burden in Peyers patches, leading to focal inflammation, and identifies specific AIEC traits required for niche colonization and immunopathology.

This study shows that gut and oral bacteria metabolize peanut allergens, affecting IgE-binding and anaphylaxis severity in allergic individuals.

This study identifies cis-aconitate as a dual-action antiviral and anti-inflammatory agent that reduces influenza mortality in mice by targeting viral polymerase and ERK/AKT/NF-κB signaling.

This study shows that bowel preparation with PEG increases susceptibility to pathogens and exacerbates inflammation in mouse and in vitro models.

The paper investigates how human milk components interact with infant genomics to affect gut microbiota and risk of childhood asthma and atopy.

This study identifies the Pel polysaccharide as a driver of autoaggregation in S. intermedius, linking it to biofilm formation and increased pathogenicity.

The paper investigates microbial engraftment after FMT by analyzing multiple patients from a single donor and identifies a unique set of engrafted genes in responders.

This study identifies innate immune signaling and CD11b+CD11c+CD103+ cell migration to the brain as mechanisms linking microbial colonization to behavioral changes in mice.

The paper shows that ExsA regulates the Fem system in Pseudomonas aeruginosa, linking it to virulence factors and affecting pathogenicity in vivo.

This paper introduces micro-plaque assays to improve phage isolation and characterization, showing they can isolate 21 unique phages from one sample and identify phage susceptibility in clinical strains.

This study shows that Medroxyprogesterone Acetate (MPA) increases vaginal microbiota diversity and reduces glycogen and amylase, which correlates with increased HIV-1 susceptibility in Kenyan sex workers and humanized mice.

This study shows that high-fat diet during pregnancy alters maternal gut microbiota and barrier function, leading to placental hypoxia and fetal gut developmental issues.