Teresita Padilla‐Benavides

Tceal7 is a BRG1-regulated target of calcineurin signaling that promotes myoblast differentiation

This study identifies TCEAL7 as a BRG1-regulated target of calcineurin signaling that promotes myoblast differentiation and reveals its role in myogenic gene regulation.

Iron-endoplasmic reticulum-extracellular matrix axis regulates cancer cell invasion

This study shows that loss of DMT1 disrupts iron homeostasis, leading to ER stress and ECM destabilization, which enhances cancer cell invasion in 3D models.

A periplasmic metallochaperone (PmcY) couples Zn2+-transport to sensing in Pseudomonas aeruginosa

The paper identifies PA3962 as a periplasmic metallochaperone (PmcY) that couples Zn2+ transport to sensing in Pseudomonas aeruginosa, regulating OprD expression and imipenem sensitivity.

CuiT is a Cu importer required for metal homeostasis in Salmonella enterica

This study identifies CuiT as a key copper importer in Salmonella enterica, showing its role in copper homeostasis, gene regulation, and stress adaptation.

Reciprocal regulation between the protein arginine deiminases and mSWI/SNF chromatin remodelers controls skeletal muscle differentiation and regeneration

This study shows PADs and mSWI/SNF chromatin remodelers reciprocally regulate each other's expression and function in skeletal muscle differentiation and regeneration.

Cell Death Induced by Homoisoflavonoid Brazilin and its Semi-synthetic Derivates on MDA-MB-231 and MCF7 Breast Cancer Cell Lines

This study evaluates the pro-apoptotic effects of Brazilin and its derivatives on breast cancer cell lines, showing selective induction of mitochondrial stress and cell death in triple-negative cells.

The PBAF chromatin remodeling complex contributes to metal homeostasis through Mtf1 regulation

The paper shows that the PBAF chromatin remodeling complex regulates metal homeostasis in myoblasts via Mtf1, with metal supplementation compensating for some complex deficiencies.

Cysteine Rich Intestinal Protein 2 is a copper-Responsive regulator of skeletal muscle differentiation.

This study identifies mCrip2 as a copper-responsive regulator of skeletal muscle differentiation through functional and biochemical analyses in murine myoblasts.

Muscle-Specific Pyruvate Kinase Isoforms, Pkm1 and Pkm2, Regulate Mammalian SWI/SNF Proteins and Histone 3 Phosphorylation During Myoblast Differentiation

This study shows that Pkm2 and Pkm1 regulate chromatin remodeling and histone phosphorylation during myoblast differentiation by affecting mSWI/SNF subunits and histone modifications.

Differential requirements for different subfamilies of the mammalian SWI/SNF chromatin remodeling enzymes in myoblast differentiation

The paper investigates the roles of three mSWI/SNF subfamilies in myoblast differentiation, finding distinct requirements for BAF and ncBAF complexes, while PBAF is dispensable.

Calcineurin broadly regulates the initiation of skeletal muscle-specific gene expression by binding target promoters and facilitating the interaction of the SWI/SNF chromatin remodeling enzyme

This study identifies four temporal patterns of calcineurin-dependent gene expression during skeletal muscle differentiation and shows Cn promotes gene expression by facilitating chromatin remodeling and transcription factor interactions.