Author

Hannah M. Binfet

Pacific Northwest National Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Athena SchepmoesiD· 1 shared Chinemerum P. Ogbu· 1 shared Christy S. NiemeyeriD· 1 shared Isaac Kwame AttahiD· 1 shared James E. HasselliD· 1 shared John MelchioriD· 1 shared Katelyn M. BakeriD· 1 shared Kayla G. SprengeriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Athena SchepmoesORCID

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1 paper

Recent·Most cited

ApoE Lipidation State Directs Immunometabolic Reprogramming of Human Microglia

Tsion G. Shiferaw, Snigdha Sarkar, Katelyn M. Baker, Rowan S. Wooldridge, Hannah M. Binfet, Victoria N. Prozapas, Chinemerum P. Ogbu, Athena Schepmoes, Isaac Kwame Attah, Christy S. Niemeyer, Kayla G. Sprenger, James E. Hassell, Robert H. Eckel, John Melchior, Kimberley D. Bruce

This study shows that ApoE4 lipidation state affects human microglial metabolism and function, with lipid-bound ApoE4 causing metabolic reprogramming and lipid-free ApoE4 inducing inflammatory signaling.

bioRxiv · May 7, 2026 · PreprintNeuroscience