Author

Hannah Wendorff

Johns Hopkins University

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Biochemistry· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander Strom· 1 shared Brendan AntiochosiD· 1 shared Jacob Lueck· 1 shared Jasper MohiD· 1 shared Jungsan SohniD· 1 shared Shuai Wu· 1 shared Stephanie Torres· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Alexander Strom

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1 paper

Recent·Most cited

Dimerization-dependent gel-like condensation with dsDNA underpins the activation of human cGAS

Jacob Lueck, Alexander Strom, Stephanie Torres, Shuai Wu, Jasper Moh, Hannah Wendorff, Brendan Antiochos, Jungsan Sohn

This study shows that cGAS dimerization on dsDNA forms gel-like condensates, which activate cGAS and protect dsDNA, while single-stranded RNA can dissolve these condensates.

Cell Reports · Jan 23, 2026Peer-reviewedBiochemistry