Hans Brunnström

Histology-guided 3D virtual staining of microCT-imaged lung tissue via deep learning

This paper develops a deep learning method to virtually stain 3D microCT lung tissue, mimicking histological stains and enabling 3D pathology analysis.

Multi-omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

The paper identifies metabolites and genes associated with squamous cell lung cancer using multi-omic data and validates their expression in tumors and cell lines.

TCR clonality and TCR clonal expansion in the in situ microenvironment of non-small cell lung cancer

This study links TCR clonality in NSCLC to genetic mutations, immune phenotypes, immunotherapy response, and patient survival.

Shared heritability and functional enrichment across six solid cancers

This study quantifies genetic correlations between six solid cancers and other diseases using GWAS data, finding shared heritability and functional enrichment in regulatory regions.