Gapless assembly of complete human and plant chromosomes using only nanopore sequencing
Sergey Koren, Zhigui Bao, Andrea Guarracino, Shujun Ou, Sara Goodwin, Katharine M. Jenike, Julian Lucas, Brandy McNulty, Jimin Park, Mikko Rautiainen, Arang Rhie, Dick Roelofs, Harrie Schneiders, Ilse Vrijenhoek, Koen Nijbroek, , Adam M. Phillippy
This paper demonstrates that ONT Duplex sequencing combined with Pore-C data can assemble complete, high-quality human and plant chromosomes with base accuracy over 99.999%.
Genome Research · Nov 1, 2024Peer-reviewedBioinformatics