Author

Alexander H. J. Wittenberg

KeyGene (Netherlands)ORCID 0000-0002-0482-2592Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:whole-genome sequencing· 5 Research Focus:genome assembly· 4 Organism:fungi (other)· 2 Organism:plant (other)· 2 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

Harrie Schneiders· 4 shared Koen Nijbroek· 3 shared Andreas PeiliD· 2 shared Henryk FlachowskyiD· 2 shared Ilse Vrijenhoek· 2 shared Janne LempeiD· 2 shared Jens KeilwageniD· 2 shared Katharina J. HoffiD· 2 shared

Activity by Year

2016-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenomics

Harrie Schneiders

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5 papers

Recent·Most cited

Gapless assembly of complete human and plant chromosomes using only nanopore sequencing

Sergey Koren, Zhigui Bao, Andrea Guarracino, Shujun Ou, Sara Goodwin, Katharine M. Jenike, Julian Lucas, Brandy McNulty, Jimin Park, Mikko Rautiainen, Arang Rhie, Dick Roelofs, Harrie Schneiders, Ilse Vrijenhoek, Koen Nijbroek, , Adam M. Phillippy

This paper demonstrates that ONT Duplex sequencing combined with Pore-C data can assemble complete, high-quality human and plant chromosomes with base accuracy over 99.999%.

Genome Research · Nov 1, 2024Peer-reviewedBioinformatics

Segmental Duplications Drive the Evolution of Accessory Regions in a Major Crop Pathogen

Anouk C. van Westerhoven, Carolina Aguilera-Gálvez, Giuliana Nakasato‐Tagami, Xiaoqian Shi‐Kunne, Einar Martínez de la Parte, Edgar A. Chavarro‐Carrero, H.J.G. Meijer, Alice Feurtey, Nani Maryani, Nadia Ordonez, Harrie Schneiders, Koen Nijbroek, Alexander H. J. Wittenberg, R. Hofstede, Fernando A. García-Bastidas, , Michael Seidl

This study shows that segmental duplications drive the evolution of accessory regions in Fusarium oxysporum, contributing to virulence evolution in banana pathogens.

New Phytologist · Feb 25, 2024Peer-reviewedGenomics

The structure of the tetraploid sour cherry 'Schattenmorelle' (Prunus cerasus L.) genome reveals insights into its segmental allopolyploid nature

Thomas Wöhner, Ofere Francis Emeriewen, Alexander H. J. Wittenberg, Koen Nijbroek, Rui Peng Wang, Evert-Jan Blom, Harrie Schneiders, Jens Keilwagen, Thomas Berner, Katharina J. Hoff, Lars Gabriel, Hannah Thierfeldt, Omar Almolla, Lorenzo Barchi, Mirko Schuster, , Henryk Flachowsky

The paper sequences and analyzes the genome of the sour cherry cultivar Schattenmorelle to reveal its segmental allopolyploid structure and evolutionary history.

Frontiers in Plant Science · Dec 1, 2023Peer-reviewedGenomics

The draft chromosome-level genome assembly of tetraploid ground cherry (Prunus fruticosa Pall.) from long reads

Thomas Wöhner, Ofere Francis Emeriewen, Alexander H. J. Wittenberg, Harrie Schneiders, Ilse Vrijenhoek, J. Halász, K. Hrotkó, Katharina J. Hoff, Lars Gabriel, Janne Lempe, Jens Keilwagen, Thomas Berner, Mirko Schuster, Andreas Peil, Jens Norbert Wünsche, , Henryk Flachowsky

The paper presents a chromosome-level genome assembly of tetraploid ground cherry using long-read sequencing technology and reports annotated genes and plastid sequences.

Genomics · Nov 1, 2021Peer-reviewedGenomics

The megabase-sized fungal genome of Rhizoctonia solani assembled from nanopore reads only.

Erwin Datema, Raymond Jozef Maurinus Hulzink, Lisanne Blommers, Jose Espejo Valle-Inclán, Nathalie J. van Orsouw, Alexander H. J. Wittenberg, Martin de Vos

This paper presents the first nanopore-only assembly of the ~54 MB genome of Rhizoctonia solani, demonstrating improved contiguity through optimized DNA isolation and sequencing.

bioRxiv · Nov 1, 2016 · PreprintGenomics