Non-Genetic Mechanisms of Fractional Resistance to Abemaciclib in Dedifferentiated Liposarcoma.
Lauryn E. Bailey, Samuel C. Wolff, Tarek M. Zikry, Garrett A. Sessions, Austin A. Whitman, Elizaveta K. Titerina, Hayden Raish, Joal D. Beane, Jeremy E. Purvis, Philip M. Spanheimer
The paper identifies non-genetic resistance mechanisms in dedifferentiated liposarcoma to abemaciclib by analyzing cell-cycle regulators in cell lines and patient samples.
bioRxiv · May 26, 2026 · PreprintCancer Biology