Author
University of North Carolina at Chapel HillORCID 0000-0003-3360-249XUnclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Garrett A. Sessions, Tarek M. Zikry, Lauryn E. Bailey…·Brian O. Diekman
This study finds that female OA synovial fibroblasts show higher senescence markers and reduced oxidative stress response compared to males.
Lauryn E. Bailey, Samuel C. Wolff, Tarek M. Zikry…·Philip M. Spanheimer
The paper identifies non-genetic resistance mechanisms in dedifferentiated liposarcoma to abemaciclib by analyzing cell-cycle regulators in cell lines and patient samples.
Sonja Mihailovic, Samuel C. Wolff, Katarzyna M. Kedziora…·Jeremy E. Purvis
This study uses CRISPR/Cas9 and microraft arrays to track OCT4, SOX2, and NANOG dynamics in human stem cells during differentiation, revealing spatiotemporal patterns in germ layer formation.
Chantel L. Martin, Cavin K Ward-Caviness, Radhika Dhingra…·Allison E. Aiello
This study examines how neighborhood conditions relate to epigenetic aging using DNA methylation clocks in a sample of 158 individuals from the Detroit Neighborhood Health Study.
Samuel C. Wolff, Katarzyna M. Kedziora, Raluca Dumitru…·Jeremy E. Purvis
The paper shows that OCT4 inheritance predetermines fate choice in human embryonic stem cells, with higher OCT4 ratios in daughters leading to sustained pluripotency and reduced differentiation potential.