Author

Joal D. Beane

The Ohio State UniversityORCID 0000-0002-4160-4340Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alessandro La FerlitaiD· 2 shared Alex C. KimiD· 2 shared Manoj H. Palavalli· 2 shared Ashwini Kumar EsnakulaiD· 1 shared Aslam M. EjaziD· 1 shared Austin A. WhitmaniD· 1 shared Elizaveta K. TiterinaiD· 1 shared Garrett A. SessionsiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

Alessandro La FerlitaORCID

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3 papers

Recent·Most cited

Non-Genetic Mechanisms of Fractional Resistance to Abemaciclib in Dedifferentiated Liposarcoma.

Lauryn E. Bailey, Samuel C. Wolff, Tarek M. Zikry, Garrett A. Sessions, Austin A. Whitman, Elizaveta K. Titerina, Hayden Raish, Joal D. Beane, Jeremy E. Purvis, Philip M. Spanheimer

The paper identifies non-genetic resistance mechanisms in dedifferentiated liposarcoma to abemaciclib by analyzing cell-cycle regulators in cell lines and patient samples.

bioRxiv · May 26, 2026 · PreprintCancer Biology

Upregulation of GREB1 in colorectal cancer ovarian metastases may be a potential therapeutic target

Samantha M. Ruff, Alessandro La Ferlita, Manoj H. Palavalli, Joal D. Beane, Susan Tsai, Oliver S. Eng, Alex C. Kim, Ashwini Kumar Esnakula

The paper identifies GREB1 as upregulated in colorectal cancer ovarian metastases compared to peritoneal metastases and primary tumors, suggesting it as a potential hormonal therapeutic target.

bioRxiv · Aug 31, 2025 · PreprintCancer Biology

TWIST1 mediated transcriptional activation of SPON2 drives colorectal peritoneal metastasis through activation of cancer-associated fibroblast signaling network

Zhuan Zhou, Alessandro La Ferlita, Manoj H. Palavalli, Xiongfeng Chen, Lauren A. Tyler, Aslam M. Ejaz, Joal D. Beane, Patricio Marcelo Polanco, Huocong Huang, Alex C. Kim

This study identifies the SPP1-TWIST1-SPON2 signaling axis as a driver of colorectal peritoneal metastasis through cancer-associated fibroblast signaling.

bioRxiv · Apr 11, 2025 · PreprintCancer Biology