Scalable and deep profiling of mRNA targets for individual microRNAs with chimeric eCLIP
Sergei A. Manakov, Alexander A. Shishkin, Brian A. Yee, Kylie A. Shen, Diana Cox, Samuel S. Park, Heather M Foster, Karen B. Chapman, Gene Wei-Ming Yeo, Eric L. Van Nostrand
This paper introduces chimeric eCLIP, a method to efficiently profile miRNA:mRNA interactions at scale, showing significant improvements in recovery and specificity.
bioRxiv · Feb 13, 2022 · PreprintGenomics