Samuel S. Park

This study maps SARS-CoV-2 protein-RNA interactions using eCLIP, revealing new regulatory sites for viral replication and translation.

This study shows that silica nanoshell degradation in biological environments affects SERRS signal strength, with pH playing a key role in nanoparticle stability and performance.

This paper creates a high-resolution spatial transcriptomic atlas of the human basal ganglia, identifying 60 cell types and their spatial organization across multiple nuclei.

The paper identifies optimal RNA base editors for RBP-RNA interaction studies by evaluating over thirty rBEs using PRINTER framework.

This paper identifies circHIPK3 as a competing endogenous RNA that sequesters IGF2BP2 to regulate target mRNAs, including STAT3, and shows its correlation with bladder cancer survival.

HydRA predicts RNA-binding capacity using protein interaction and sequence data, identifying novel RNA-binding domains with high specificity and sensitivity.

This paper introduces chimeric eCLIP, a method to efficiently profile miRNA:mRNA interactions at scale, showing significant improvements in recovery and specificity.

The paper identifies circRNA-RBP interactions in cancer, showing their role in circRNA biogenesis and cancer gene expression, with implications for bladder cancer prognosis.

The paper analyzes eCLIP data for 150 RBPs in K562 and HepG2 cells, revealing binding modalities, RBP functions, and novel RNA processing mechanisms.