Author

Hee Lam Chan

ProQR Therapeutics (Netherlands)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:multiome· 1 Organism:non-human primate· 1 Assay:proteomics· 1

Frequent Co-Authors

Cathaline den Besten· 1 shared Erik de VriezeiD· 1 shared Erwin van WijkiD· 1 shared Gerard J. PlatenburgiD· 1 shared Hanka VenselaariD· 1 shared Hannie KremeriD· 1 shared Hester C. van DiepeniD· 1 shared Iris A. E. SchulkensiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Cathaline den Besten

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1 paper

Recent·Most cited

Antisense oligonucleotide-based treatment of retinitis pigmentosa caused by USH2A exon 13 mutations

Kalyan Dulla, Ralph W. N. Slijkerman, Hester C. van Diepen, Sílvia Albert, Margo Dona, Wouter Beumer, Janne J. Turunen, Hee Lam Chan, Iris A. E. Schulkens, Lars Vorthoren, Cathaline den Besten, Levi C.M. Buil, Iris Schmidt, Jiayi Miao, Hanka Venselaar, , Erwin van Wijk

This study demonstrates that QR-421a induces exon 13 skipping in USH2A transcripts, restoring retinal function in zebrafish and non-human primates.

Molecular Therapy · Apr 23, 2021Peer-reviewedGenetics