Author

Hester C. van Diepen

Leiden University Medical CenterORCID 0000-0002-0796-9223Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Organism:human· 1 Organism:mouse· 1 Assay:multiome· 1

Frequent Co-Authors

Ashna Ramkisoensing· 1 shared Cathaline den Besten· 1 shared Dominique CioccaiD· 1 shared Erik de VriezeiD· 1 shared Erwin van WijkiD· 1 shared Étienne ChalletiD· 1 shared Gerard J. PlatenburgiD· 1 shared Hanka VenselaariD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Ashna Ramkisoensing

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2 papers

Recent·Most cited

Physical activity increases neuronal activity in the circadian clock of diurnal Arvicanthis ansorgei

Rosanna Caputo, Robin A. Schoonderwoerd, Ashna Ramkisoensing, Jan A. M. Janse, Hester C. van Diepen, Sylvie Raison, Paul Pévet, Nienke A. V. Derks, Dominique Ciocca, Tom Deboer, Étienne Challet, Johanna H. Meijer

The paper examines how physical activity affects the circadian clock in diurnal rodents, finding that activity increases SCN neuronal firing rather than suppressing it, unlike in nocturnal animals.

bioRxiv · May 31, 2022 · PreprintNeuroscience

Antisense oligonucleotide-based treatment of retinitis pigmentosa caused by USH2A exon 13 mutations

Kalyan Dulla, Ralph W. N. Slijkerman, Hester C. van Diepen, Sílvia Albert, Margo Dona, Wouter Beumer, Janne J. Turunen, Hee Lam Chan, Iris A. E. Schulkens, Lars Vorthoren, Cathaline den Besten, Levi C.M. Buil, Iris Schmidt, Jiayi Miao, Hanka Venselaar, , Erwin van Wijk

This study demonstrates that QR-421a induces exon 13 skipping in USH2A transcripts, restoring retinal function in zebrafish and non-human primates.

Molecular Therapy · Apr 23, 2021Peer-reviewedGenetics