Author

Levi C.M. Buil

ProQR Therapeutics (Netherlands)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:multiome· 1

Frequent Co-Authors

Ana Rita R. MaiaiD· 1 shared Cathaline den Besten· 1 shared Ceren H. Çitirikkaya· 1 shared Daria M. FedorushkovaiD· 1 shared Erik de VriezeiD· 1 shared Erwin van WijkiD· 1 shared Gerard J. PlatenburgiD· 1 shared Hanka VenselaariD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Ana Rita R. MaiaORCID

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2 papers

Recent·Most cited

Disconnect between in vitro and in vivo efficacy of the MPS1 inhibitor NTRC 0066-0 against glioblastoma

Mark C. de Gooijer, Daria M. Fedorushkova, Ping Zhang, Levi C.M. Buil, Ceren H. Çitirikkaya, Hilal Çolakoğlu, Ana Rita R. Maia, Irena Bočkaj, Margarita Espitia Ballestas, Laura E. Kuil, Jos H. Beijnen, Olaf van Tellingen

This study evaluates the efficacy of the MPS1 inhibitor NTRC 0066-0 against glioblastoma in vitro and in vivo, finding strong in vitro activity but no antitumor effect in mouse models.

Cellular Oncology · Feb 16, 2026Peer-reviewedCancer Biology

Antisense oligonucleotide-based treatment of retinitis pigmentosa caused by USH2A exon 13 mutations

Kalyan Dulla, Ralph W. N. Slijkerman, Hester C. van Diepen, Sílvia Albert, Margo Dona, Wouter Beumer, Janne J. Turunen, Hee Lam Chan, Iris A. E. Schulkens, Lars Vorthoren, Cathaline den Besten, Levi C.M. Buil, Iris Schmidt, Jiayi Miao, Hanka Venselaar, , Erwin van Wijk

This study demonstrates that QR-421a induces exon 13 skipping in USH2A transcripts, restoring retinal function in zebrafish and non-human primates.

Molecular Therapy · Apr 23, 2021Peer-reviewedGenetics