Author

Heidi M. Colton

Chimerix (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Asif RakibiD· 1 shared Calvin J. GordoniD· 1 shared David DuliniD· 1 shared Dean W. SellesethiD· 1 shared John C. MareckiiD· 1 shared Kevin D. RaneyiD· 1 shared Mark T. HeiseiD· 1 shared Matthias GötteiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Asif RakibORCID

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Author profile →

1 paper

Recent·Most cited

The nucleoside analog CMX521 inhibits coronavirus RNA-dependent RNA polymerase via a two-pronged mechanism

Asif Rakib, Calvin J. Gordon, Thomas K. Anderson, John C. Marecki, Quinte Smitskamp, Nathaniel J. Moorman, Mark T. Heise, Heidi M. Colton, Dean W. Selleseth, Randall Lanier, Kevin D. Raney, Robert N. Kirchdoerfer, Matthias Götte, David Dulin

This study identifies a two-pronged mechanism by which CMX521 inhibits SARS-CoV-2 RNA-dependent RNA polymerase through biochemical assays and single-molecule techniques.

Journal of Biological Chemistry · Sep 16, 2026Peer-reviewedMicrobiology