Author

Randall Lanier

Chimerix (United States)ORCID 0009-0004-3442-6015Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Asif RakibiD· 1 shared Calvin J. GordoniD· 1 shared David DuliniD· 1 shared Dean W. SellesethiD· 1 shared Heidi M. Colton· 1 shared John C. MareckiiD· 1 shared Kevin D. RaneyiD· 1 shared Mark T. HeiseiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Asif RakibORCID

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Author profile →

1 paper

Recent·Most cited

The nucleoside analog CMX521 inhibits coronavirus RNA-dependent RNA polymerase via a two-pronged mechanism

Asif Rakib, Calvin J. Gordon, Thomas K. Anderson, John C. Marecki, Quinte Smitskamp, Nathaniel J. Moorman, Mark T. Heise, Heidi M. Colton, Dean W. Selleseth, Randall Lanier, Kevin D. Raney, Robert N. Kirchdoerfer, Matthias Götte, David Dulin

This study identifies a two-pronged mechanism by which CMX521 inhibits SARS-CoV-2 RNA-dependent RNA polymerase through biochemical assays and single-molecule techniques.

Journal of Biological Chemistry · Sep 16, 2026Peer-reviewedMicrobiology