Potent photoswitch for expression of biotherapeutics in mammalian cells by light
Jeannette Gebel, Elisa Ciglieri, Rainer Stahl, Fraser Duthie, Andreas Möglich, Herbert Müller-Hartmann, Hanns-Martin Schmidt, Dagmar Wachten
The paper introduces a photoswitch called DEL-VPR that enables strong, light-induced gene expression in mammalian cells, surpassing constitutive promoters and improving protein production.
bioRxiv · Oct 3, 2024 · PreprintMolecular Biology