Andreas Möglich

The paper investigates dimer asymmetry in blue-light sensor histidine kinases by combining structural and functional analyses to reveal light-dependent conformational changes.

The paper develops an engineered living material that uses NIR light to release a pro-angiogenic peptide, promoting capillary network formation in endothelial cultures.

This paper introduces optovolution, a directed evolution method using light and cell cycle oscillations to evolve dynamic protein functionalities, and demonstrates its application in yeast.

The paper identifies traits of bathy phytochromes and develops a far-red light-activated optogenetic system called pFREDusk.

The paper studies how evolutionary changes in the BLUF domain of Rubellimicrobium mesophilum affect photodynamics and endonuclease activity, revealing a light-gated endonuclease mechanism.

This study uses rhizobial bathy-phytochromes to create synthetic two-component systems in bacteria that respond to near-infrared light for precise gene expression control.

The paper introduces a photoswitch called DEL-VPR that enables strong, light-induced gene expression in mammalian cells, surpassing constitutive promoters and improving protein production.

This study investigates the reduction midpoint potential of AsLOV2 and shows that methionine substitutions increase E0 and reduce light sensitivity.

The paper introduces a method to optogenetically control regulatory RNA molecules by engineering chimeric RNAs that interact with a light-sensitive protein, enabling precise spatial and temporal regulation of gene expression.