Author
University of BonnORCID 0000-0002-7896-8703Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Stefan Ebner, Kshiti Meera Phulphagar, Yubell Alvarez…·Felix Meissner
The paper shows NLRP3 activators disrupt the AP2 complex and impair plasma membrane signaling, leading to inflammation and cell death.
Jeannette Gebel, Elisa Ciglieri, Rainer Stahl…·Dagmar Wachten
The paper introduces a photoswitch called DEL-VPR that enables strong, light-induced gene expression in mammalian cells, surpassing constitutive promoters and improving protein production.
Wei Wang, Alesja Dernst, Bianca Martin…·M. S. J. Mangan
The paper shows that butyrate and propionate activate the NLRP3 inflammasome in human macrophages when combined with TLR agonists, through HDAC inhibition and epigenetic changes.