GeneticsbioRxivPreprint
Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics
Ersin Akıncı, Minsun Cha, Lin Lin…·Richard I. Sherwood
This study identifies genetic pathways involved in remdesivir cytotoxicity using CRISPR-Cas9 screening and transcriptomics, finding that SLC29A3 and AK2 are key factors in toxicity and efficacy.
31 citations