Author

Larissa Cardoso Zanetti

Brigham and Women's HospitalORCID 0000-0003-1716-7301Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Benyapa KhowpinitchaiiD· 1 shared Callie J. DonahueiD· 1 shared Christopher A. CassaiD· 1 shared Ersin AkıncıiD· 1 shared Grace Hui Ting YeoiD· 1 shared Heysol C. Bermudez-Cabrera· 1 shared James D. FifeiD· 1 shared Lin Lin· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Benyapa KhowpinitchaiORCID

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1 paper

Recent·Most cited

GeneticsbioRxivPreprintAug 27, 2020

Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics

Ersin Akıncı, Minsun Cha, Lin Lin…·Richard I. Sherwood

This study identifies genetic pathways involved in remdesivir cytotoxicity using CRISPR-Cas9 screening and transcriptomics, finding that SLC29A3 and AK2 are key factors in toxicity and efficacy.

31 citations

humanCRISPR screen

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