Author

Hicham Affia

Centre Hospitalier Universitaire Sainte-Justine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Grégor AndelfingeriD· 2 shared Séverine LeclerciD· 2 shared Anant Bahadur PateliD· 1 shared Andrew T. Song· 1 shared Bidisha Chattopadhyaya· 1 shared Denise Carrier· 1 shared Derek N. RobertsoniD· 1 shared Élie HaddadiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Grégor AndelfingerORCID

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Author profile →

2 papers

Recent·Most cited

Enhancing adult neuroplasticity by epigenetic regulation of Parvalbumin-expressing GABAergic cells

Marisol Lavertu-Jolin, Bidisha Chattopadhyaya, Pegah Chehrazi, Denise Carrier, Florian Wünnemann, Séverine Leclerc, Félix Dumouchel, Derek N. Robertson, Hicham Affia, Kamal Saba, Vijaya Gopal, Anant Bahadur Patel, Grégor Andelfinger, Graciela Piñeyro, Graziella Di Cristo

This study shows that reducing Hdac2 in PV+ cells enhances fear memory extinction in adults by downregulating Acan, a perineuronal net component.

Molecular Psychiatry · May 2, 2023Peer-reviewedNeuroscience

Developmental role of macrophages modelled in human pluripotent stem cell derived intestinal tissue

Andrew T. Song, Renata Sindeaux, Yuanyi Li, Hicham Affia, Tapan Agnihotri, Séverine Leclerc, Patrick Piet Van Vliet, Mathieu Colas, Jean-Victor Guimond, Natasha Patey, Jean‐Sébastien Joyal, Élie Haddad, Luis Bruno Barreiro, Grégor Andelfinger

The paper develops a human intestinal organoid model with macrophages to study their role in development, finding that macrophages regulate metabolism and growth without affecting tissue architecture.

bioRxiv · Sep 9, 2022 · PreprintDevelopmental Biology