Author

Hiroshi Shitara

Tokyo Metropolitan Institute of Medical Science

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Akinori EndoiD· 1 shared Daichi SadatoiD· 1 shared Hayato HiraiiD· 1 shared Hideya KawajiiD· 1 shared Hiroko Masuda· 1 shared Hiroyuki SasanumaiD· 1 shared Ichiro TaniuchiiD· 1 shared Junko MuraiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCell Biology

Akinori EndoORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

BRCA2 loss triggers a downward spiral of genomic instability via ROS-dependent metabolic collapse

Hayato Hirai, Tomohiro Iguchi, Kenji Kitajima, Kosuke Yamazaki, Daichi Sadato, Kosuke Tanegashima, Yutaka Kanoh, Hiroko Masuda, Saori Wakasa, Manami Sano, Ryotaro Kawasumi, Kosei Yamada, Shintaro Yamada, Akinori Endo, Noriko Nakatsugawa, , Hiroyuki Sasanuma

This paper shows BRCA2 loss causes genomic instability through ROS-dependent metabolic collapse, highlighting the role of glutathione metabolism and PARP inhibitors in cell death.

bioRxiv · May 21, 2026 · PreprintCell Biology