Author
Tokyo Metropolitan Institute of Medical ScienceORCID 0000-0002-0878-1628Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Hayato Hirai, Tomohiro Iguchi, Kenji Kitajima…·Hiroyuki Sasanuma
This paper shows BRCA2 loss causes genomic instability through ROS-dependent metabolic collapse, highlighting the role of glutathione metabolism and PARP inhibitors in cell death.
Kosuke Yamazaki, Tomohiro Iguchi, Yutaka Kanoh…·Hiroyuki Sasanuma
This study investigates how acetaldehyde-induced DNA damage is repaired, finding that homologous recombination and TDP1/TDP2 play critical roles in repair efficiency.
Yutaka Kanoh, Seiji Matsumoto, Masaru Ueno…·Hisao Masai
This study shows that Rif1 overexpression in fission yeast causes mitotic defects and cell death by altering chromatin localization at the nuclear periphery.