Author

Holly H. Guo

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Arin B. AuroraiD· 1 shared Ashley Leach· 1 shared Deepak NijhawaniD· 1 shared Divya ReddyiD· 1 shared Jan Peter ErzbergeriD· 1 shared Jef K. De BrabanderiD· 1 shared Jiwoong KimiD· 1 shared Johann PetersoniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Arin B. AuroraORCID

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Author profile →

1 paper

Recent·Most cited

A small molecule inhibitor of NVL suppresses tumor growth by blocking ribosome biogenesis

Holly H. Guo, Ye Tao, Victor Emmanuel Cruz, Min Fang, Vishal Khivansara, Shanhai Xie, Ashley Leach, Divya Reddy, Johann Peterson, Jiwoong Kim, Noelle Sevilir Williams, Arin B. Aurora, Jan Peter Erzberger, Jef K. De Brabander, Deepak Nijhawan

The paper identifies NVL as a target for cancer therapy, showing that its inhibition by MM17 and MM927 suppresses tumor growth through ribosome biogenesis disruption.

bioRxiv · Jul 31, 2025 · PreprintBiochemistry