Author
The University of Texas Southwestern Medical CenterORCID 0000-0001-6253-4268Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Shilpa Singh, Catherine E. Gleason, Min Fang…·Matthew G. Oser
This paper develops cyclin A/B macrocyclic inhibitors that induce apoptosis in cancers with high E2F activity by blocking RxL-mediated interactions, showing efficacy in SCLC models.
Holly H. Guo, Ye Tao, Victor Emmanuel Cruz…·Deepak Nijhawan
The paper identifies NVL as a target for cancer therapy, showing that its inhibition by MM17 and MM927 suppresses tumor growth through ribosome biogenesis disruption.
Tingyi Wanyan, Ling Cai, Deepak Nijhawan…·Yang Xie
This paper introduces MIDI, a model that predicts cancer drug response and explains drug-target interactions using an attention mechanism, outperforming existing methods in prediction and interpretability.