Author

Holly Hathrell

University of Oxford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Jonathan GodwiniD· 3 shared Shankar SrinivasiD· 3 shared Xin LüiD· 3 shared Felix ZhouiD· 2 shared Jens RittscheriD· 2 shared Matthew J. StoweriD· 2 shared Anna Vincent· 1 shared B. Christoffer LagerholmiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersDevelopmental Biology

Jonathan GodwinORCID

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3 papers

Recent·Most cited

Quantitative multi-scale morphodynamic analysis reveals ratchet-like collective DVE migration and epiblast retrograde cell flow during anterior patterning in the mouse embryo

Matthew J. Stower, Felix Y. Zhou, Rahil Valani, Jan Rozman, Holly Hathrell, Jonathan Godwin, Xin Lü, Jens Rittscher, Julia M. Yeomans, Shankar Srinivas

bioRxiv · Apr 28, 2026 · PreprintDevelopmental Biology

Single-cell phenomics reveals behavioural and mechanical heterogeneities underpinning collective migration during mouse anterior patterning

Matthew J. Stower, Felix Zhou, Holly Hathrell, Jason Yeung, Shifaan Thowfeequ, Jonathan Godwin, Falk Schneider, B. Christoffer Lagerholm, Marco Fritzsche, Jeyan Thiyagalingam, Xin Lü, Jens Rittscher, Shankar Srinivas

The paper uses single-cell phenomics to study DVE cell migration in mouse embryos, revealing mechanical heterogeneities and how surrounding cells facilitate collective migration.

bioRxiv · Mar 31, 2023 · PreprintDevelopmental Biology

ASPP2/PP1 complexes maintain the integrity of pseudostratified epithelia undergoing remodelling during morphogenesis

Christophe Royer, Elizabeth Sandham, Elizabeth A. Slee, Jonathan Godwin, Nisha Veits, Holly Hathrell, Felix Zhou, Karolis Leonavicius, Jemma Garratt, Tanaya Narendra, Anna Vincent, Céline Jones, Tim J. Child, Kevin Coward, Chris Graham, , Shankar Srinivas

This study identifies the ASPP2/PP1 complex as critical for maintaining pseudostratified epithelial integrity during morphogenesis by preventing apical delamination and supporting F-actin organization.

bioRxiv · Nov 3, 2020 · PreprintDevelopmental Biology