Author

Shifaan Thowfeequ

University of OxfordORCID 0000-0002-5716-428XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:differential expression· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Felix ZhouiD· 3 shared Shankar SrinivasiD· 3 shared Jonathan GodwiniD· 2 shared Matthew J. StoweriD· 2 shared Xin LüiD· 2 shared Antonio ScialdoneiD· 1 shared B. Christoffer LagerholmiD· 1 shared Bart VanhaesebroeckiD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersDevelopmental Biology

Felix ZhouORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintNov 14, 2024

Calcium signalling is required for anterior patterning in the mouse embryo

Matthew J. Stower, Richard C. V. Tyser, Shifaan Thowfeequ…·Shankar Srinivas

The paper investigates the role of calcium signaling in anterior-posterior axis formation in the mouse embryo, finding that SERCA inhibition disrupts DVE migration and axial patterning.

DOI 10.1101/2024.11.14.623160

mouseimaging

𝕏 PostBluesky

Developmental BiologyDevelopmental CellPeer-reviewedJun 5, 2024

Characterisation of the transcriptional dynamics underpinning the function, fate, and migration of the mouse Anterior Visceral Endoderm

Shifaan Thowfeequ, Jonathan Fiorentino, Di Hu…·Shankar Srinivas

The paper characterizes the transcriptional dynamics of the mouse Anterior Visceral Enderm (AVE) during migration and identifies Ephrin- and Semaphorin-signalling as critical for its movement.

25 citations

mousescRNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintMar 31, 2023

Single-cell phenomics reveals behavioural and mechanical heterogeneities underpinning collective migration during mouse anterior patterning

Matthew J. Stower, Felix Zhou, Holly Hathrell…·Shankar Srinivas

The paper uses single-cell phenomics to study DVE cell migration in mouse embryos, revealing mechanical heterogeneities and how surrounding cells facilitate collective migration.

12 citations

mousespatial transcriptomics

𝕏 PostBluesky