Marco Fritzsche

This paper develops a method to isolate and characterize SMAPs from NK-92 cells, showing their cytotoxic activity against tumor cells in vitro and in vivo.

The paper identifies anterograde actin waves that move antigen-engaged microclusters away from the cSMAC, revealing a dual actin dynamics mechanism in T cell immunological synapses.

This study uses a biomimetic system to show that E-cadherin mobility on lipid bilayers influences actin polymerization, leading to distinct actin architectures during adherens junction formation.

The paper uses single-cell phenomics to study DVE cell migration in mouse embryos, revealing mechanical heterogeneities and how surrounding cells facilitate collective migration.

This paper introduces miSFITs, synthetic microRNA response elements that allow precise control of gene expression levels in mammalian cells, showing their utility in modulating antigen expression in a mouse melanoma model.