NeurosciencebioRxivPreprint
Transduction catalysis:doxorubicin accelerates and enhances rAAV-mediated gene expression in the cortex of mouse, cat and monkey
Hongliang Gong, Nini Yuan, Zhiming Shen…·Wei Wang
This study shows doxorubicin enhances rAAV-mediated gene expression in the cortex of mice, cats, and monkeys, with effects observed across multiple serotypes and without significant cytotoxicity.