Jihong Wu

LOGO is a lightweight language model for interpreting non-coding regions of the human genome, achieving improved performance in promoter identification and enhancer-promoter interaction prediction.

The paper identifies a splice variant of the GHRHR receptor that mediates constitutive signal bias towards β-arrestin recruitment, impacting downstream signaling pathways in prostate cancer cells.

This study shows doxorubicin enhances rAAV-mediated gene expression in the cortex of mice, cats, and monkeys, with effects observed across multiple serotypes and without significant cytotoxicity.

This paper introduces a phenotype-specific framework to identify causative nonsynonymous variants in eye abnormalities, achieving high accuracy and precision in pathogenicity prediction.