Barrier Immune Memory is Promoted by Intestinal Epithelial Cell Presentation of Injected Bacterial Antigens
Christopher Garrett Wilson, Pragun Acharya, Laura Karsch, Lennard Wayne Duck, Nana Twumasi-Ankrah, Yuanyou Wang, Hongxing Shen, Chuan Xing, Blake F. Frey, Vishal H. Oza, Stacey N. Harbour, Yoshiko Nagaoka-Kamata, Jeffrey R. Singer, Robin D. Hatton, Jeffrey R. Moffitt, , Casey Todd Weaver
The paper shows that CD4 T cell memory is enhanced when antigens are presented by intestinal epithelial cells rather than bacterial proteins.
bioRxiv · Mar 31, 2026 · PreprintImmunology