Author

Carlene L. Zindl

University of Alabama at BirminghamORCID 0000-0003-4841-3552Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Blake F. FreyiD· 2 shared Casey Todd WeaveriD· 2 shared Yoshiko Nagaoka-Kamata· 2 shared Asif Elahi· 1 shared Awalpreet Singh ChadhaiD· 1 shared Caleb R. GlassmaniD· 1 shared Christopher Garrett Wilson· 1 shared Chuan Xing· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Blake F. FreyORCID

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2 papers

Recent·Most cited

IL-23 Licenses Pathogenic Th17 Transdifferentiation via STAT4-dependent Upregulation of IL-12Rβ2

Awalpreet Singh Chadha, Asif Elahi, Blake F. Frey, Yoshiko Nagaoka-Kamata, Carlene L. Zindl, Trenton R. Schoeb, Caleb R. Glassman, K. Christopher García, Casey Todd Weaver

This paper shows IL-23 licenses Th17 cells for transdifferentiation into pathogenic effectors by upregulating IL-12Rβ2 via STAT4, revealing a stepwise mechanism involving IL-23 and IL-12.

bioRxiv · Jul 26, 2026 · PreprintImmunology

Barrier Immune Memory is Promoted by Intestinal Epithelial Cell Presentation of Injected Bacterial Antigens

Christopher Garrett Wilson, Pragun Acharya, Laura Karsch, Lennard Wayne Duck, Nana Twumasi-Ankrah, Yuanyou Wang, Hongxing Shen, Chuan Xing, Blake F. Frey, Vishal H. Oza, Stacey N. Harbour, Yoshiko Nagaoka-Kamata, Jeffrey R. Singer, Robin D. Hatton, Jeffrey R. Moffitt, , Casey Todd Weaver

The paper shows that CD4 T cell memory is enhanced when antigens are presented by intestinal epithelial cells rather than bacterial proteins.

bioRxiv · Mar 31, 2026 · PreprintImmunology