Author

Hsin-Pei Lee

National Cancer Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Organism:human· 2 Research Focus:spatial domain detection· 2 Assay:spatial transcriptomics· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:electronic health records· 1

Frequent Co-Authors

Darko CastveniD· 2 shared Jens Uwe MarquardtiD· 2 shared Lichun MaiD· 2 shared Maria Olga HernandeziD· 2 shared Marshonna ForguesiD· 2 shared Meng LiuiD· 2 shared Wenqi WuiD· 2 shared Anuradha BudhuiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Darko CastvenORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell type-centric interaction networks define spatial architecture of intrahepatic cholangiocarcinoma

Hsin-Pei Lee, Meng Liu, Wenqi Wu, Ngoc Thao Lam Nguyen, Jittiporn Chaisaingmongkol, Darko Castven, Ethan Levy, Noémi Kedei, Maria Olga Hernandez, Manjari Kundu, Marshonna Forgues, Man‐Hsin Hung, Anuradha Budhu, Nada Alani, Stephen M. Hewitt, , Lichun Ma

This study defines the spatial architecture of intrahepatic cholangiocarcinoma using single-cell spatial proteomics and a graph-based deep learning framework to identify multicellular spatial patterns and their association with patient outcomes.

bioRxiv · Jun 6, 2026 · PreprintCancer Biology

Tumor cell villages define the co-dependency of tumor and microenvironment in liver cancer

Meng Liu, Maria Olga Hernandez, Darko Castven, Hsin-Pei Lee, Wenqi Wu, Limin Wang, Marshonna Forgues, Jonathan M. Hernandez, Jens Uwe Marquardt, Lichun Ma

The paper uses spatial single-cell data to identify tumor cell clusters (villages) and their microenvironmental dependencies, showing their impact on patient outcomes.

Nature Communications · Feb 21, 2026Peer-reviewedCancer Biology

Phase-Dependent Stimulation of the Hippocampus: A Computational Modeling Approach

Hsin-Pei Lee, Toren Arginteanu, Paweł Kudela, William Stanley Anderson, Yousef Salimpour

This study uses a computational model to show phase-dependent stimulation can modulate theta-gamma coupling in the hippocampus, with implications for treating memory disorders.

bioRxiv · Sep 14, 2024 · PreprintNeuroscience