The abscopal effect of Combination IRE with anti-PD-1 achieves local ablation and systemic control of PDAC
Qizhen Cao, Zhenzhen Xun, Yitao Tang, Jiakai Hou, Boping Jing, Ping Pan, Jing Zhang, Shiaw-Yih Lin, Sanjay Gupta, Jared K. Burks, Huanmin Wang, James P. Long, Han Liang, Weiyi Peng, Chun Li
This paper shows that combining IRE with anti-PD-1 induces abscopal effects in PDAC by triggering immune activation and systemic antitumor responses.
bioRxiv · May 7, 2026 · PreprintImmunology