Cell BiologybioRxivPreprint
The epithelial-specific ER stress sensor IRE1β enables host-microbiota crosstalk to affect colon goblet cell development
M. J. Grey, H. De Luca, D. V. Ward…·W. I. Lencer
This study shows IRE1β is essential for microbiota-induced goblet cell maturation and mucus barrier assembly in the colon, shaping gut microbiota composition through ER stress regulation.
DOI 10.1101/2021.07.28.453864