Author

J. R. Turner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Immunology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:development & morphogenesis· 2

Frequent Co-Authors

A. S. Verkman· 2 shared M. Donowitz· 2 shared A. Guimera Brunet· 1 shared A. Gupta· 1 shared A. Kapoor· 1 shared B. A. McCormick· 1 shared C. Jung· 1 shared C. Madre· 1 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersCell Biology

A. S. Verkman

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Author profile →

7 papers

Recent·Most cited

Distinct steady-state properties and TNF responses of epithelial long myosin light chain kinase (MLCK) splice variants

S. D. Chanez-Paredes, S. Abtahi, J. Zha, L. Zuo, W. He, J. R. Turner

The paper identifies the Ig3 domain of MLCK1 as critical for perijunctional localization and barrier function, showing it can limit TNF-induced barrier loss in Crohn's disease.

bioRxiv · Oct 13, 2022 · PreprintCell Biology

Quantitative dose-response analysis untangles host bottlenecks to enteric infection

I. W. Campbell, K. Hullahalli, J. R. Turner, M. K. Waldor

This study quantifies how host bottlenecks affect the founding population of Citrobacter rodentium during infection, showing that microbiota and dose influence pathogen establishment.

bioRxiv · Oct 11, 2022Microbiology

Epithelial monolayer development and tight junction assembly on nanopillar arrays

J. Yeste, X. Illa, N. Shashikanth, A. Guimera Brunet, R. Villa, J. R. Turner

This study shows that nanopillar arrays can be used to culture mature epithelial monolayers with tight junctions intact, by positioning nanopillars in lateral intercellular spaces.

bioRxiv · Mar 9, 2022 · PreprintCell Biology

The epithelial-specific ER stress sensor IRE1β enables host-microbiota crosstalk to affect colon goblet cell development

M. J. Grey, H. De Luca, D. V. Ward, I. A. M. Kreulen, S. E. Foley, J. R. Thiagarajah, B. A. McCormick, J. R. Turner, W. I. Lencer

This study shows IRE1β is essential for microbiota-induced goblet cell maturation and mucus barrier assembly in the colon, shaping gut microbiota composition through ER stress regulation.

bioRxiv · Jul 28, 2021 · PreprintCell Biology

Human Rotavirus Diarrhea Is Associated with Altered Trafficking and Expression of Apical Membrane Transport Proteins

N. C. Zachos, N. W. Baetz, A. Gupta, A. Kapoor, R. N. Cole, A. S. Verkman, J. R. Turner, M. K. Estes, M. Donowitz

bioRxiv · Sep 26, 2019 · PreprintCell Biology

Nod2 protects remote small intestinal sites in case of colonic inflammation.

J.-P. Hugot, Z. Al Nabhani, D. Berrebi, C. Martinez-Vinson, N. Montcuquet, G. Dietrich, G. Singh, J. R. Turner, C. Madre, M. Roy, E. Ogier-Denis, M. Dussaillant, N. Cerf-Bensussan, H. Zouali, C. Jung, , F. Barreau

The paper shows that NOD2 prevents small intestinal inflammation in areas remote from colonic injury in mice.

bioRxiv · Jan 3, 2019 · PreprintImmunology

cAMP stimulates SLC26A3 activity in human colon by a CFTR-dependent mechanism that does not require CFTR activity

C.-M. Tse, J. Yin, V. Singh, R. Sarker, R. Lin, A. S. Verkman, J. R. Turner, M. Donowitz

bioRxiv · Aug 20, 2018Physiology