Author

I. A. Prior

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Approach:experimental assay· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. J. Beckett· 2 shared A. Acosta-Serrano· 1 shared A. Casas-Sanchez· 1 shared A. M. Johansen· 1 shared B. Middlehurst· 1 shared C. Rose· 1 shared C. S. Fonseca· 1 shared C. Solorzano· 1 shared

Activity by Year

2016-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. J. Beckett

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Ras protein abundance correlates with Ras isoform mutation patterns in cancer.

F. E. Hood, Y. M. Sahraoui, R. E. Jenkins, I. A. Prior

The paper quantifies Ras protein abundance across cell lines and tissues, finding KRAS>NRAS>>HRAS expression patterns that correlate with mutation frequencies in cancer.

bioRxiv · Nov 4, 2021Cancer Biology

Trypanosoma brucei colonises the tsetse gut via an immature peritrophic matrix in the proventriculus

C. Rose, N. A. Dyer, A. Casas-Sanchez, A. J. Beckett, C. Solorzano, B. Middlehurst, M. Marcello, M. J. Lehane, I. A. Prior, A. Acosta-Serrano

This study shows Trypanosoma brucei colonizes the tsetse gut via the immature peritrophic matrix in the proventriculus, not directly through the midgut PM.

bioRxiv · Jan 7, 2019Microbiology

Fibroblast Growth Factor 2 lethally sensitizes cancer cells to stress-targeted therapeutic inhibitors

M. H. Dias, C. S. Fonseca, J. D. Zeidler, L. L. Albuquerque, M. S. da Silva, E. Cararo-Lopes, M. S. Reis, V. Noel, I. A. Prior, H. A. Armelin

This study shows that FGF2 sensitizes cancer cells to stress-targeted therapies by disrupting homeostasis and inducing synthetic lethal interactions with proteasome or DNA damage inhibitors.

Molecular Oncology · Dec 3, 2018Peer-reviewedCancer Biology

Microtubule organization within mitotic spindles revealed by serial block face scanning EM and image analysis

F. M. Nixon, T. R. Honnor, G. P. Starling, A. J. Beckett, A. M. Johansen, J. A. Brettschneider, I. A. Prior, S. J. Royle

The paper describes a correlative light-SBF-SEM workflow to analyze microtubule organization in mitotic spindles and introduces computational tools to study their spatial arrangement.

bioRxiv · Nov 15, 2016Cell Biology