A. Acosta-Serrano

Tsetse flies choose birthing sites guided by environmental but not pheromonal cues

This study shows that tsetse flies select larviposition sites based on environmental cues, not pheromonal signals like n-pentadecane.

Protein N-glycosylation is essential for SARS-CoV-2 infection

This study shows that host and viral N-glycosylation are essential for SARS-CoV-2 infection, with inhibition reducing infectivity and virion production.

Tsetse salivary glycoproteins are modified with paucimannosidic N-glycans, are recognised by C-type lectins and bind to trypanosomes

The paper characterizes the N-glycan profile of tsetse salivary glycoproteins and shows they bind trypanosomes and are recognized by C-type lectins.

Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis

This study shows that nitisinone can kill tsetse flies without harming bees, offering an eco-friendly method to control African trypanosomiasis transmission.

Insights into the salivary N-glycome of Lutzomyia longipalpis, vector of visceral leishmaniasis

This study characterizes the N-glycan profile of Lutzomyia longipalpis saliva, identifying oligomannose structures and a novel 144 Da modification.

Gut-associated bacteria invade the midgut epithelium of Aedes aegypti and stimulate innate immunity and suppress Zika virus infection in cells.

This study shows gut bacteria invade mosquito cells, activate immune pathways, and reduce Zika virus infection.

Trypanosoma brucei colonises the tsetse gut via an immature peritrophic matrix in the proventriculus

This study shows Trypanosoma brucei colonizes the tsetse gut via the immature peritrophic matrix in the proventriculus, not directly through the midgut PM.

The crystal structure and localization of Trypanosoma brucei invariant surface glycoproteins suggest a more permissive VSG coat in the tsetse-transmitted metacyclic stage

The paper identifies and characterizes a novel family of invariant surface proteins in the metacyclic stage of Trypanosoma brucei, suggesting a more permissive VSG coat structure that may aid vaccine development.